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Clinical data
Trade namesCymbalta, others [1]
License dataEU  EMA:  by INN, US   FDA: duloxetine
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth
Drug classSerotonin–norepinephrine reuptake inhibitor
ATC codeN06AX21 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability~ 50% (32% to 80%)
Protein binding~ 95%
MetabolismLiver, two P450 isozymes, CYP2D6 and CYP1A2
Elimination half-life12 hours
Excretion70% in urine, 20% in feces

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Cymbalta all product namesariclaim, delok, deloxi, duloxetin, duloxetina, duloxetinum, duxetin, duzela, xeristar, yentreve
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Duloxetine should not be used in cost of cymbalta at costco with a monoamine oxidase inhibitor MAOI such as phenelzine Nardil tranylcypromine Parnate isocarboxazid Marplan and selegiline Eldepryl or within 14 days of discontinuing the MAOI. At cost of cymbalta at costco 5 days should be allowed after stopping duloxetine before starting an MAOI.It is important to take thismedication exactly as prescribed by your doctor to ensure that you are gettingthe maximum benefit from the medication.

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