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|Trade names||Cymbalta, others |
|License data||EU EMA: by INN, US FDA: duloxetine|
|Pregnancy category||AU: B3 US: C (Risk not ruled out)|
|Routes of administration||By mouth|
|Drug class||Serotonin–norepinephrine reuptake inhibitor|
|ATC code||N06AX21 ( WHO )|
|Legal status||AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only|
|Bioavailability||~ 50% (32% to 80%)|
|Protein binding||~ 95%|
|Metabolism||Liver, two P450 isozymes, CYP2D6 and CYP1A2|
|Elimination half-life||12 hours|
|Excretion||70% in urine, 20% in feces|
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|Cymbalta all product names||ariclaim, delok, deloxi, duloxetin, duloxetina, duloxetinum, duxetin, duzela, xeristar, yentreve|
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