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Clinical data
PronunciationSee note at tretinoin
Trade namesAccutane (originator), others [1]
License dataUS   FDA: Isotretinoin
Pregnancy categoryAU: X (High risk) US: X (Contraindicated)
Routes of administrationBy mouth, topical
ATC codeD10AD04 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding99.9%
Elimination half-life10–20 hours
ExcretionRenal and fecal

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My doctor was a well-known, famous and accomplished dermatologist in Greece.32 Isotretinoin use can rarely lead to a more severe form of acne, acne fulminans.

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Exactly 14 days into this drug was when things started to take a turn.cbi.

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You may report side effects to the FDA at 1-800-FDA-1088.In April of 2016 he was diagnosed with pancreatic cancer. Pathology came back with Autoimmune chronic pancreatitis.

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