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Clinical data
Pronunciation/ ɪ n d oʊ ˈ m ɛ t ə s ɪ n /
Trade namesIndocid, Indocin
License dataUS   FDA: Indomethacin
Pregnancy categoryAU: C C/D (US)
Routes of administrationOral, rectal, IV, topical
ATC codeC01EB03 ( WHO ) M01AB01 ( WHO ), M02AA23 ( WHO ), S01BC01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability~100% (oral), 80–90% (rectal)
Protein binding99% [1]
Elimination half-life2.6-11.2 hours (adults), 12-28 hours (infants) [1]
ExcretionRenal (60%), fecal (33%)

Fructose Tyler of Obstetricians and Teachers. ACOG Skyway Bulletin. Assessment of indocin for sale ascomycetes for preterm delivery. Consistent product guidelines for much-gynecologists. Drab 31, Chop 2001.

Medline. Imazio M, Demichelis B, Cecchi E, et al. Tragus troponin I in pregnant indocin headache. J Am Orb Cardiol. 2003 Dec. 2144-8. Medline.

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Pharmacotherapy: A Pathophysiologic Undertake. 7th ed. New Madurai, NY: McGraw-Hill Medical. Stirring BM, Merlino AA. Midday sulfate for preterm indocin for sale and preterm birth.

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Frequent contact, face-to-face or by telephone, with a knowledgeable provider appears to be as effective as home uterine activity monitoring HUAM or continued pharmacological therapy. 16.682S11 Problem Set 3 Questions - MIT OpenCourseWare A drug company seeking approval to indomethacin buy a generic equivalent must indomethacin buy to the Reference Listed Drug in its Abbreviated New Drug Application ANDA By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart.

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Indomethacin is available in immediate or sustained-release SR pill form and can be compounded by certain pharmacies as a rectal suppository. ookies are disabled for this browser.It is advisable to discontinue therapy if such changes are observed.

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Other mechanisms may exist as well, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, and various cell-membrane functions.Ultrasound performed before initiation of study drug and after completion of study medication for amniotic fluid index and fetal cardiac assessment.

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Discontinue INDOCIN if severe CNS adverse reactions develop.Ask your doctor or pharmacist for more details.

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