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|Pronunciation||/ ˌ ɛ s oʊ ˈ m ɛ p r ə ˌ z oʊ l, - ˈ m iː -, - ˌ z ɒ l / |
|Trade names||Nexium, others |
|License data||EU EMA: by INN, US FDA: Esomeprazole|
|Pregnancy category||AU: B3 US: C (Risk not ruled out)|
|Routes of administration||By mouth, IV|
|Drug class||proton pump inhibitor|
|ATC code||A02BC05 ( WHO )|
|Legal status||AU: S2 (Pharmacy only) UK: General sales list (GSL, OTC) US: OTC|
|Bioavailability||50 to 90%|
|Metabolism||Liver (CYP2C19, CYP3A4)|
|Elimination half-life||1–1.5 hours|
|Excretion||80% Kidney 20% Faecal|
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This diarrhea may be caused by an infection Clostridium difficile in the intestines.Other enzymes related to beta-amyloid proteins may also be affected by the drugs in the brain.
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When using NEXIUM consider alternative anti-platelet nexium 40 nebenwirkungen treatment with any acid-suppressing medications over a long period of time eg, longer than 3 years may lead to malabsorption of cyanocobalamin vitamin B12 Rare reports nexium 40 nebenwirkungen cyanocobalamin deficiency occurring with acid-suppressing therapy have been reported in the literature Hypomagnesemia has been reported rarely with prolonged treatment with PPI therapy and may require decrease esomeprazole concentrations.
Avoid concomitant use of NEXIUM with St. John's wort or Literature suggests that concomitant use of PPIs with methotrexate primarily at high dose; see methotrexate prescribing information may elevate and prolong serum levels of methotrexate and/or its metabolite, possibly leading to methotrexate toxicities.Taking the wrong product could harm you.
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