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Dexamethasone
Clinical data
AHFS/Drugs.comMonograph
MedlinePlusa682792
License dataEU  EMA:  by INN
Pregnancy categoryAU: A US: C (Risk not ruled out)
Routes of administrationBy mouth, IV, IM, SC, IO
ATC codeA01AC02 ( WHO ) C05AA09 ( WHO ), D07AB19 ( WHO ), D10AA03 ( WHO ), H02AB02 ( WHO ), R01AD03 ( WHO ), S01BA01 ( WHO ), S02BA06 ( WHO ), S03BA01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability80–90%
Protein binding77%
MetabolismLiver
Elimination half-life190 minutes (3.2 hours)
ExcretionUrine (65%)

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  1. Dexamethasone product names: aacidexam, acicot, afacort, alegi, alerdex, alfalyl, ampidexalone, ampimycine dex, amumetazon, aphtasolon, apidex, axidexa, azium, baycuten-n, biométhasone, bisuo ds, bralifex plus, brulin, camidexon, cebedex, celudex, chibro-cadron, chondron dexa, colsamin, colvasone, corsona, cortamethasone, corti biciron, corticetine, cortidex, cortidexason, cresophene, d-cort, decadronal, decafos, decalona, decamin, decason, decasone, decdan, decilone, decobel, decordex, decorex, decorten, decortil, dectancyl, dekort, deksamet, deksametazonas, deltafluorene, depodexafon, dermadex, dermatt, dersone, desamix neomicina, desashock, dexa, dexa-ct, dexa-sine, dexabene, dexabeta, dexachel, dexacip, dexacol, dexacollyre, dexacom, dexacort, dexacortal, dexadreson, dexafar, dexaflam, dexafort, dexafree, dexafrin, dexagalen, dexagel, dexagent-ophthal, dexagenta, dexagil, dexagrane, dexahexal, dexaject, dexalaf, dexalergin, dexalin, dexalocal, dexalone, dexaltin, dexamed, dexamedis, dexamedium, dexamedix, dexamedron, dexameral, dexamet, dexametasona, dexameth, dexamethason, dexaméthasone, dexamethasonum, dexamethazon, dexamin, dexam
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    If such an anaphylactoid reaction occurs, the following measures are recommended: immediate slow intravenous injection of 0. -0.When corticosteroids are administered concomitantly with potassium-depleting diuretics, patients should be observed closely for development of hypokalemia. Intra-articular injection of a corticosteroid may produce systemic as well as local effects.

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