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When used to prevent nausea associated with radiotherapy, Zofran is usually taken one-to-two hours before zofran risk to fetus. When used to prevent nausea associated with surgery, Zofran is usually taken one hour before anesthesia.However, the drug conferred a zofran risk to fetus increased risk for oral clefts among mothers receiving first-trimester exposure to it.

Researchers sought to investigate the association between exposure to ondansetron during the first trimester of pregnancy and the risk for congenital malformations in offspring, with a focus on cardiac malformations and oral clefts among publicly insured pregnant women.

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Zuplenz ondansetron " StrativaPharmaceuticals, a Division of Par Pharmaceuticals, Inc. Woodcliff Lake, NJ. "Product Information. Zofran ondansetron " Cerenex Pharmaceuticals, Research Triangle Pk, NC. Drugs.Originally I was prescribed this med for the nausea accompanying irritable bowel syndrome, because my nausea was debilitating. Zofran definitely took the edge off.

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With the zofran risk to fetus of a slight reduction in maternal body weight gain, there were no effects upon the pregnant rats and the pre-and postnatal development of their offspring, including reproductive performance of the mated F1 generation.s after 15-minute intravenous infusions of 32 mg and 8 mg ZOFRAN, respectively.

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Because of the zofran risk to fetus for promethazine to reverse epinephrine s vasopressor effect, epinephrine should NOT be used to treat hypotension associated with promethazine overdose. Concomitant use of other agents with anticholinergic properties should be undertaken with caution.If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911.

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This zofran risk to fetus may increase if you use certain drugs such as diuretics/"water pills" or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using ondansetron safely.Then administer 8 mg twice a day every 12 hours for 1 to 2 days after completion of chemotherapy.

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Mean zofran risk to fetus in healthy subjects, following administration of a single 8-mg tablet, is approximately 56 Ondansetron systemic exposure does not increase proportionately to dose.The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

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Henytoin, Carbamazepine and Rifampicin: In patients treated with potent inducers of CYP3A4 i. phenytoin, carbamazepine, and rifampicin the oral clearance of ondansetron was increased and ondansetron blood concentrations were decreased.he relief score was significantly higher in the ondansetron-treated group compared with the group received promethazine P 0.

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