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When used to prevent nausea associated with radiotherapy, Zofran is usually taken one-to-two hours before zofran risk to fetus. When used to prevent nausea associated with surgery, Zofran is usually taken one hour before anesthesia.However, the drug conferred a zofran risk to fetus increased risk for oral clefts among mothers receiving first-trimester exposure to it.
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With the zofran risk to fetus of a slight reduction in maternal body weight gain, there were no effects upon the pregnant rats and the pre-and postnatal development of their offspring, including reproductive performance of the mated F1 generation.s after 15-minute intravenous infusions of 32 mg and 8 mg ZOFRAN, respectively.
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Because of the zofran risk to fetus for promethazine to reverse epinephrine s vasopressor effect, epinephrine should NOT be used to treat hypotension associated with promethazine overdose. Concomitant use of other agents with anticholinergic properties should be undertaken with caution.If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911.
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This zofran risk to fetus may increase if you use certain drugs such as diuretics/"water pills" or if you have conditions such as severe sweating, diarrhea, or vomiting. Talk to your doctor about using ondansetron safely.Then administer 8 mg twice a day every 12 hours for 1 to 2 days after completion of chemotherapy.
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Henytoin, Carbamazepine and Rifampicin: In patients treated with potent inducers of CYP3A4 i. phenytoin, carbamazepine, and rifampicin the oral clearance of ondansetron was increased and ondansetron blood concentrations were decreased.he relief score was significantly higher in the ondansetron-treated group compared with the group received promethazine P 0.
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